Firefighters in Sault Ste. Marie spent the night battling a second major fire in the downtown area in less than two weeks.

This time it turned deadly when an adult entertainment nightclub and some apartments went up in flames.

Police say a man in his 60's died in hospital from injuries sustained in this fire. 

Firefighters had to use hundreds of gallons of water in battling the blaze, which broke out after 11 pm Sunday.

Peter Johnson is the chief for Sault Ste. Marie Fire Services.

"Crews responded here before midnight of last night and encountered a heavy fire. Crews attempted to do an interior attack and eventually had to pull back due to the significant amount of fire and amount of water we had to use to try and extinguish the fire. At that point, it was deemed not safe for our crews to be inside." said Johnson.

Fire officials say the scene has now been turned over to Sault Ste. Marie police.

"We have an agreement with the police service and the Ontario Fire Marshal, any type of extensive fire like this, we activate our agreement. We call the Ontario Fire Marshal in and they work jointly with the local police service and complete an in depth investigation, and that's what's taking place at this time." said Johnson.

This is the second major fire in the Sault in less than two weeks.

The fire chief says battling fires in the winter is taxing on the crew and the equipment, but he says firefighters have performed admirably.

The last 11 days have been busy for the local Canadian Red Cross as well. It is an agency that helps people displaced from their homes due to disaster or emergency.

Diane Lajambe is a manager at the Canadian Red Cross in Sault Ste. Marie.

"Well, it certainly has been. The last couple weeks we've assisted 16 people to find emergency shelter. Normally, we respond in Sault Ste. Marie and surrounding area to house fires. As you know, we don't have house fires every week." said Lajambe.

The agency can help provide emergency lodging, food, and clothing for up to 72 hours for those affected.